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MicroSight® MSI 1-step HRM Analysis for Microsatellite Instability

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Laboratory analysis at PentaBase



Assays | Cancer diagnosis and stratification

PlentiPlex™ MSI

PlentiPlex™ MSI enables a validated screening for microsatellite instability in Tumors. The test works as an aid to assist in further cancer treatments, which provides more personalised and precise treatment for the individual.

Specifications Details
INTENDED USE OF PlentiPlex™ MSI

PlentiPlex™ MSI assays are intended for evaluation of impaired mismatch repair (MMR) and the resulting microsatellite instability affecting prognosis and selection of treatment in cancer patients. PlentiPlex™ MSI assays offer two different multiplexed MSI assays for the length analysis of five microsatellite loci. This makes PlentiPlex™ MSI assays valuable stratification tools for assisting cancer treatment planning.

Advantages of PlentiPlex™ MSI:

Simple MSI stratification of solid tumors for treatment guidance

Simplified four-step workflow

Well-known validated loci

Minimal hands-on time

Instructions for Use: PlentiPlex™ MSI
PUT YOUR HEALTH FIRST

An aid to the oncologist's treatment planning

The test will provide an assessment of the presence of microsatellite instability in well-known validated loci used in the clinic to detect DNA mismatch repair deficiency (dMMR). Immune checkpoint inhibitors have been shown to be effective among colorectal cancer patients with dMMR tumors.

Other Assays

2

Formats

5

Loci

2

Configurations

1

Solution

Product information

Format
Ready-to-use
Version
Multiplex
Loci
BAT25, BAT26, D2S123, D5S346, D17S250, NR-22 and NR-24, MONO27
Mutation Assay
Mutation assay primer/probe mix
Master mix
Shipment
≤ -20°C or on Dry ice
Storage
Maximum -20°C
Storage time
12 months from manufacturing data and no longer than the indicated expiration date.
Result time
≤ Three hours
Sample type
DNA from FFPE samples
Intended use
CE IVD
Compatible Instruments for use with PlentiPlex™ MSI assays

PentaBase systems for analysis

The PlentiPlex™ MSI assays are now designed and validated to be used on BaseTyper™48(PentaBase PCR instrument) and the following instruments:

Rotor-Gene (Qiagen)

MX3000P/3005P (Agilent)

LightCycler® 96 + 480 (Roche)

CFX96TM (Bio-Rad)

ABI 7500/7900HT (Applied Biosystems)

MIC (Bio Molecular Systems)

MyGo Pro (IT-IS Life Science)

BaseTyper™48
Distributor celloxa Distributor Anachem Greec/Cyprus Distributor Dynex Distributor AmpliTech Distributor Ridacom Distributor Resnova
Sponsor and collaborator
How to order

PlentiPlex™ MSI assay

Are you interested in our assays for screening microsatellite instability in cancerous cells? Find a local distributor, become our distributor or order your assay at PentaBase directly.

Order with PentaBase Order from your local distributor Become distributor
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