Waldenström Lymphoma qPCR Assay

PlentiPlex_™ MYD88

A highly sensitivity qPCR assay for detection of the MYD88 L265P mutation, used as an aid in the stratification of lymphoma subtypes.

Specifications Details

Introduction to PlentiPlex™ MYD88

PlentiPlex™ MYD88 Waldenström Lymphoma qPCR Assay utilises PentaBase’s unique DNA chemistry, known as Intercalating Nucleic Acid (INA™) which vastly increases both affinity and specificity of assay oligonucleotides towards the target region compared to assays based on standard DNA chemistries.

The obtained results of PlentiPlex™ MYD88 Waldenström Lymphoma qPCR Assay are intended for identification of the presence of the MYD88 L265P, facilitating discrimination between Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) and non-Hodgkin lymphoma

Advantages of PlentiPlex™ MYD88 :

Results in less than two hours

Open platform design

High sensitivity due to INA™ chemistry

Minimal hands-on time

Instructions for Use: PlentiPlex™ MYD88

PUT YOUR HEALTH FIRST

An aid to personalised cancer treatment planning

The PlentiPlex™ MYD88 L265P Assay will provide a simple, fast and sensitive aid in the diagnosis of Waldenström lymphoma, with a limit of detection (LoD) down to 0.6% and 0.75% mutation in whole blood and formalin-fixed paraffin-embedded (FFPE) samples. The assay is designed for open platforms allowing for maximal laboratory equipment flexibility.

Other Assays

Hour result time

Configurations

Solution

Product information

Please refer to the IFU for acceptable sample type and collection device combinations.

Format

Ready-to-use and Dispense-ready

Version

Simplex

Mutation targeted

Mutation in codon 265 of the Myeloid differentiation primary response 88 protein (MYD88 L265P)

Shipment

≤ -20°C or on Dry ice

Storage

Maximum -20°C (In original packaging)

Storage time

12 months from manufacturing data and no longer than the indicated expiration date.

Result time

≤ Two hours

Sample type

gDNA extracted from FFPE

Detection sensitivity

0.25% of a human genomic DNA (gDNA) sample

Intended use

RUO

Approved Instruments for Use of PlentiPlex™ MYD88 assays

PentaBase systems for analysis

The PlentiPlex™ MYD88 Waldenström Lymphoma qPCR assay is now designed and validated to be used on BaseTyper™48.4(PentaBase PCR instrument) and the following instruments:

Rotor-Gene (Qiagen)

MX3000P/3005P (Agilent)

CFX96TM (Bio-Rad)

ABI 7500/7900HT (Applied Biosystems)

MIC (Bio Molecular Systems)

MyGo Pro (IT-IS Life Science)

BaseTyper™48

How to order