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Laboratory analysis at PentaBase



Waldenström Lymphoma qPCR Assay

PlentiPlex™ MYD88

A highly sensitivity qPCR assay for detection of the MYD88 L265P mutation, used as an aid in the stratification of lymphoma subtypes.

Specifications Details
Introduction to PlentiPlex™ MYD88

PlentiPlex™ MYD88 Waldenström Lymphoma qPCR Assay utilises PentaBase’s unique DNA chemistry, known as Intercalating Nucleic Acid (INA™) which vastly increases both affinity and specificity of assay oligonucleotides towards the target region compared to assays based on standard DNA chemistries.

The obtained results of PlentiPlex™ MYD88 Waldenström Lymphoma qPCR Assay are intended for identification of the presence of the MYD88 L265P, facilitating discrimination between Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) and non-Hodgkin lymphoma

Advantages of PlentiPlex™ MYD88 :

Results in less than two hours

Open platform design

High sensitivity due to INA™ chemistry

Minimal hands-on time

Instructions for Use: PlentiPlex™ MYD88
PUT YOUR HEALTH FIRST

An aid to personalised cancer treatment planning

The PlentiPlex™ MYD88 L265P Assay will provide a simple, fast and sensitive aid in the diagnosis of Waldenström lymphoma, with a limit of detection (LoD) down to 0.6% and 0.75% mutation in whole blood and formalin-fixed paraffin-embedded (FFPE) samples. The assay is designed for open platforms allowing for maximal laboratory equipment flexibility.

Other Assays

2

Hour result time

2

Configurations

1

Solution

Product information

Please refer to the IFU for acceptable sample type and collection device combinations.
Format
Ready-to-use and Dispense-ready
Version
Simplex
Mutation targeted
Mutation in codon 265 of the Myeloid differentiation primary response 88 protein (MYD88 L265P)
Shipment
≤ -20°C or on Dry ice
Storage
Maximum -20°C (In original packaging)
Storage time
12 months from manufacturing data and no longer than the indicated expiration date.
Result time
≤ Two hours
Sample type
gDNA extracted from FFPE
Detection sensitivity
0.25% of a human genomic DNA (gDNA) sample
Intended use
RUO
Approved Instruments for Use of PlentiPlex™ MYD88 assays

PentaBase systems for analysis 

The PlentiPlex™ MYD88 Waldenström Lymphoma qPCR assay is now designed and validated to be used on BaseTyper™48.4(PentaBase PCR instrument) and the following instruments:

Rotor-Gene (Qiagen)

MX3000P/3005P (Agilent)

CFX96TM (Bio-Rad)

ABI 7500/7900HT (Applied Biosystems)

MIC (Bio Molecular Systems)

MyGo Pro (IT-IS Life Science)

BaseTyper™48
Distributor celloxa Distributor Anachem Greec/Cyprus Distributor Dynex Distributor AmpliTech Distributor Ridacom Distributor Resnova
Sponsor and collaborator
How to order

PlentiPlex™ MYD88 Waldenström Lymphoma qPCR Assay

Are you interested in our assays for diagnosing and differentiating between types of lymphoma? Find a local distributor, become our distributor, or order your assay at PentaBase directly.

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