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Laboratory analysis at PentaBase

Monday 16. May 2022 by Aminat Makhauri

World´s first DNA methylation assay without pre-treatment

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PentaBase´s IVDR transition

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References - BaseBlocker™

Genetic characterization of MYD88-mutated lymphoplasmacytic lymphoma in comparison with MYD88-mutated chronic lymphocytic leukemia, Baer et al. 2017, Leukemia 31, 1355–1362

References PentAdapters

Integrative Genomics Outlines a Biphasic Glucose
Response and a ChREBP-RORg Axis Regulating Proliferation in beta Cells, Schmidt et al. 2016, Cell Rep. 2016 Aug 30;16(9):2359-72

Circulating tumor DNA shows variable clonal response of breast cancer during neoadjuvant chemotherapy, Kim et al. 2017, Oncotarget. Sep 23;8(49):86423-86434

Characterization of background noise in capture-based targeted sequencing data, PArk et al. 2017, Genome Biol. Jul 21;18(1):136

Utility of targeted deep sequencing for detecting circulating tumor DNA in pancreatic cancer patients, Park et al. 2018, Sci Rep. Aug 2;8(1):11631

Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication, Reverón-Gómez et al. 2018, Mol Cell. Oct 18;72(2):239-249.e5

Genetic and epigenetic variation in 5S ribosomal RNA genes reveals genome dynamics in Arabidopsis thaliana, Simon et al. 2018, Nucleic Acids Res. Apr 6;46(6):3019-3033

References - Customized Assays

Genetic Alterations within the DENND1A Gene in Patients with Polycystic Ovary Syndrome (PCOS), Eriksen et al. 2013, PLoS ONE 8(9), e77186

References - Custom Oligonucleotides

Prevalence and genotypes of Borrelia burgdorferi sensu lato infection in Ixodes ricinus ticks in southern Norway, Kjelland et al. 2010, Scand J Infect Dis. Aug;42(8):579-585

MDM2 facilitates adipocyte differentiation through
CRTC-mediated activation of STAT3, Hallenborg et al. 2016, Cell Death Dis. Jun 30;7(6):e2289

KRAS genotyping by digital PCR combined with melting curve analysis, Tanaka et al. 2019, Sci Rep, Feb 22;9(1):2626

Discovery of a divergent HPIV4 from respiratory secretions using second and third generation metagenomic sequencing, Alquezar-Planas et al. 2013, Sci Rep.3:2468

References - IVD Assays

SensiScreen®KRAS exon 2-sensitive simplex and multiplex real-time PCR-based assays for detection of KRAS exon 2 mutations, Riva et al. 2017, PLoS ONE, Jun 21;12(6):e0178027

PlentiPlex™ Mastocytosis CE IVD, Kristensen et al. 2020, Allergy

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