PlentiPlex™ KIT Mastocytosis qPCR Assay provides a fast and easy evaluation of the presence of the KIT D816V mutation to assist in the diagnosis of Mastocytosis.
Assays | Cancer diagnosis and stratification
PlentiPlex™ KIT Mastocytosis qPCR Assay provides a fast and easy evaluation of the presence of the KIT D816V mutation to assist in the diagnosis of Mastocytosis.
PlentiPlex™ Mastocytosis assay is intended for the detection of the KIT D816V mutation, which is among the WHO criteria for the diagnosis of mastocytosis. PlentiPlex™ Mastocytosis Assay utilises PentaBase’s unique DNA chemistry, known as Intercalating Nucleic Acid (INA™), which vastly increases both affinity and specificity of assay oligonucleotides towards the target region compared to assays based on standard DNA chemistries.
Advantages of PlentiPlex™ Mastocytosis:
The Assay follows WHO criteria
Applicable for large biopsies
2 formats (Ready-to-use & Dispense ready)
Enables further personalised cancer treatment
If provided with sufficient input of DNA of sufficient quality, PlentiPlex™ Mastocytosis can detect down to 0.01% of KIT D816V mutated gDNA in a background of wild-type gDNA. PlentiPlex™ Mastocytosisis available in two versions; Ready-to-Use for fast and easy low thoughput analyses and Dispense Ready for high throughput applications.
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Solution
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Hour result time
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Procedure
PentaBase systems for analysis
The PlentiPlex™ Mastocytosis CE IVD assays are now designed and validated to be used on BaseTyper™48.4(PentaBase PCR instrument) and the following instruments:
Rotor-Gene (Qiagen)
MX3000P/3005P (Agilent)
LightCycler® 96 + 480 (Roche)
CFX96TM (Bio-Rad)
ABI 7500/7900HT (Applied Biosystems)
MIC (Bio Molecular Systems)
MyGo Pro (IT-IS Life Science)
Are you interested in our assays for the diagnosis of the Matocytosis condition? Find a local distributor, become our distributor, or order your assay at PentaBase directly.