A highly sensitivity qPCR assay for detection of the MYD88 L265P mutation, used as an aid in the stratification of lymphoma subtypes.
Waldenström Lymphoma qPCR Assay
A highly sensitivity qPCR assay for detection of the MYD88 L265P mutation, used as an aid in the stratification of lymphoma subtypes.
PlentiPlex™ MYD88 Waldenström Lymphoma qPCR Assay utilises PentaBase’s unique DNA chemistry, known as Intercalating Nucleic Acid (INA™) which vastly increases both affinity and specificity of assay oligonucleotides towards the target region compared to assays based on standard DNA chemistries.
The obtained results of PlentiPlex™ MYD88 Waldenström Lymphoma qPCR Assay are intended for identification of the presence of the MYD88 L265P, facilitating discrimination between Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) and non-Hodgkin lymphoma
Advantages of PlentiPlex™ MYD88 :
Results in less than two hours
Open platform design
High sensitivity due to INA™ chemistry
Minimal hands-on time
The PlentiPlex™ MYD88 L265P Assay will provide a simple, fast and sensitive aid in the diagnosis of Waldenström lymphoma, with a limit of detection (LoD) down to 0.6% and 0.75% mutation in whole blood and formalin-fixed paraffin-embedded (FFPE) samples. The assay is designed for open platforms allowing for maximal laboratory equipment flexibility.
2
Hour result time
2
Configurations
1
Solution
PentaBase systems for analysis
The PlentiPlex™ MYD88 Waldenström Lymphoma qPCR assay is now designed and validated to be used on BaseTyper™48.4(PentaBase PCR instrument) and the following instruments:
Rotor-Gene (Qiagen)
MX3000P/3005P (Agilent)
CFX96TM (Bio-Rad)
ABI 7500/7900HT (Applied Biosystems)
MIC (Bio Molecular Systems)
MyGo Pro (IT-IS Life Science)
Are you interested in our assays for diagnosing and differentiating between types of lymphoma? Find a local distributor, become our distributor, or order your assay at PentaBase directly.